New approach to solid phase synthesis of polyamide nucleic acids analogues (PNA) and PNA-DNA conjugates
โ Scribed by Dmitry A. Stetsenko; Elena N. Lubyako; Viktor K. Potapov; Tatyana L. Azhikima; Evgeny D. Sverdlov
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 246 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A new simple solid-phase method has been developed for synthesizing Boc-protected peptide nucleic acid (PNA) monomers. An immobilized backbone 3 was built on Expansin ยฎ resin using an ester disulphide handle: 2-hydroxypropyl-dithio-2%-isobutyric acid (HPDI). The base acetic acids of thymine 5, Z-cyt
Synthesis of a Monocharged Peptide Nucleic Acid (PNA) Analogue and Its Recognition as Substrate by DNA Polymerases. -The preparation of a novel phosphoramidite monomer based on thyminyl acetic acid coupled to a secondary nitrogen of 2-(2-amino-ethylamino)ethanol (III) is described. This monomer can