Solid phase synthesis of benzamidine-derived sulfonamide libraries
โ Scribed by Sang Woong Kim; Chang Yong Hong; Jong Sung Koh; Eun Ju Lee; Koo Lee
- Book ID
- 110276063
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 82 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1381-1991
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
An efficient protocol for the preparation of combinatorial libraries is described. The methodology first deploys solid phase chemistry to synthesize a 96-well array of intermediates linked to resin via a latent reactive functionality such as a benzyl ether, tert-amine or thioether. Cleavage from the
The solid support synthesis of a series of l-aminohydantoins based on a diverse set of hydrazino amino acids, aldehydes, and amines is described. The method involves the construction of resin attached hydrazino acid precursors, followed by subsequent derivatization, and then cyclizative cleavage off