Role of Natural Killer Cell Subsets in Cardiac Allograft Rejection
β Scribed by M. E. McNerney; K.-M. Lee; P. Zhou; L. Molinero; M. Mashayekhi; D. Guzior; H. Sattar; S. Kuppireddi; C.-R. Wang; V. Kumar; M.-L. Alegre
- Book ID
- 114803807
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 471 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1600-6135
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## Monoclonal antibody Anti Leu 7 has been used to enumerate peripheral blood N K cells in 20 renal allograft recipients. Blood was taken preoperatively and three times per week for the first month a f e r transplantation; separated mononuclear cells were stained with Anti Leu 7 then analysed on a
Natural killer" (NK) effector cells and large granular lymphocytes (LGL) are found inside rat renal allografts during rejection. Their appearance in situ precedes the appearance of cytotoxic T lymphocytes, and concomitantly with their influx in the allograft, the NK activity and the LGL are depleted