Natural killer cells can mediate cardiac allograft vasculopathy in murine allografts
β Scribed by H.S Rose; W.H Kitchens; C.M Chase; R.B Colvin; P.S Russell; J.C Madsen
- Book ID
- 117710406
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 50 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1557-3117
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## Monoclonal antibody Anti Leu 7 has been used to enumerate peripheral blood N K cells in 20 renal allograft recipients. Blood was taken preoperatively and three times per week for the first month a f e r transplantation; separated mononuclear cells were stained with Anti Leu 7 then analysed on a
Natural killer" (NK) effector cells and large granular lymphocytes (LGL) are found inside rat renal allografts during rejection. Their appearance in situ precedes the appearance of cytotoxic T lymphocytes, and concomitantly with their influx in the allograft, the NK activity and the LGL are depleted