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Role of NADPH oxidase in the apoptotic death of cultured cerebellar granule neurons

✍ Scribed by Angélica Coyoy; Antonio Valencia; Alicia Guemez-Gamboa; Julio Morán

Book ID
113630649
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
913 KB
Volume
45
Category
Article
ISSN
0891-5849

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✍ Antonio Valencia; Julio Morán 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 411 KB 👁 2 views

When cultured cerebellar granule neurons (CGN) are transferred from 25 mM KCl (K25) to 5 mM KCl (K5) caspase-3 and caspase-8, but not caspase-1 or caspase-9,activities are induced and cells die apoptotically. CGN death was triggered by a [Ca(2+)](i) modification when [Ca(2+)](i) was reduced from 300