𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Regio- and stereo-controlled synthesis of [24,30-14C]-labeled-2,3-epoxysqualene

✍ Scribed by Xiao-Yi Xiao; Glenn D. Prestwich

Publisher
John Wiley and Sons
Year
1991
Tongue
French
Weight
430 KB
Volume
29
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

[24,30‐^14^C]‐(3S)‐2,3‐Epoxysqualene and its racemate were synthesized by two convenient routes. The products have the label in a metabolically‐nonlabile position relative to the demethylation of lanosterol to cholesterol.

📜 SIMILAR VOLUMES

Synthesis of 13C- and 14C-labeled 3-(dic
Synthesis of 13C- and 14C-labeled 3-(dichloroacetyl)-5-(2-furanyl)-2,2-dimethyloxazolidine
✍ Akbar Mehrsheikh 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 287 KB 👁 1 views

Synthesis of 3-(dichloroacetyl)-5-(2-furanyl)-2,2-dimethy~oxazolidine ( common name: furilazole) labeled with carbon-14 and carbon-13 are described. Two routes for the synthesis of labeled trimethylsilyl cyanide, a precursor to furilazole, are described. One method can be carried out on milligram sc

Synthesis of 2H, 3H and 14C labelled Sch
Synthesis of 2H, 3H and 14C labelled Sch 40120
✍ D. Hesk; T. Duelfer; S. Hickey; D. Hochman; D. Koharski; P. McNamara; S. Saluja 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 376 KB

## Abstract ^2^H and ^3^H labelled Sch 40120 were prepared by Pt catalysed exchange with isotopic water. D7‐Sch 40120 was obtained in two exchanges in 53% yield and ^3^H‐Sch 40120 was prepared by a single exchange at a specific activity of 19.8 Ci/mmole. ^14^C‐Sch 40120 was prepared in 4 steps from

Synthesis of 3H, 14C and 2H4 labelled SC
Synthesis of 3H, 14C and 2H4 labelled SCH 211803
✍ D. Hesk; K. Voronin; P. McNamara; P. Royster; D. Koharski; S. Hendershot; S. Sal 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 137 KB 👁 1 views

## Abstract [^3^H]SCH 211803, at a specific activity of 1.56 Ci/mmol, was prepared by direct exchange with tritiated water and platinum metal. [^2^H~4~]SCH 211803 was prepared from [^2^H]formaldehyde in a seven step synthesis in 10% yield. [^14^C]SCH 211803 was prepared from __N__‐benzyl‐4‐hydroxy[

Synthesis and quality control of 125I-an
Synthesis and quality control of 125I-and 14C-labelled 5-iodo-2′-deoxycytidine triphosphate
✍ Ute Linz 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 French ⚖ 261 KB

## Abstract A method is described for a no‐carrier‐added synthesis and purification of doubly‐labelled [5‐^125^I, U‐^14^C]‐iododeoxycytidine triphosphate. Iodination of ^14^C‐dCTP was achieved with a radiochemical yield of 80%. Separation and purification of the reaction product were accomplished b

The synthesis of dehydro-2-norbornyl and
The synthesis of dehydro-2-norbornyl and 2-norbornyl derivatives labeled at C-3 with 14C
✍ C. C. Lee; F. L. Kung; Bo-Sup Hahn; Adrian J. Robson 📂 Article 📅 1971 🏛 John Wiley and Sons 🌐 French ⚖ 337 KB

The synthesis .from l4CC0, of various endo-and exo-3-I4Cdehydro-2-norbornyl and 2-norbornyl derivatives, suitable for use in isotopic scrambling studies, is described. ## INTRODUCTION. In the original work of Roberts and coworkers ( l , 2, on the solvolyses of exo-and end0-2,3-~~C,-2-norbornyl br