The correct use of probability distribution functions is described for the determination of mean residence time (MRT) of drug molecules in the body and is illustrated for two possible two compartment body models. A new method for estimating (MRT) is described, based on the area under the curve measu
β¦ LIBER β¦
Presystemic elimination and mean residence time
β Scribed by Dierk Brockmeier
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 94 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0142-2782
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## KEY WORDS Mean residence time MRT Moments Statistical moments Mean absorption time MAT Pharmacokinetics Pharmacodynamics Biopharmaceutic Mean residence time has been the subject of much research and discussion in recent pharmacokinetic literature. Unfortunately confusion can result from the def
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