A new definition of the mean residence time is proposed which includes the commonly used definition as a special case. The advantage of the new definition is that it applies for both linear and non-linear systems. Some practical advantages which follow from the new definition are discussed. Procedur
Types of mean residence times
โ Scribed by Dr. John G. Wagner
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 672 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0142-2782
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## KEY WORDS Mean residence time MRT Moments Statistical moments Mean absorption time MAT Pharmacokinetics Pharmacodynamics Biopharmaceutic Mean residence time has been the subject of much research and discussion in recent pharmacokinetic literature. Unfortunately confusion can result from the def
A method for calculating the mean residence times of metabolites in the body, systemic circulation, and peripheral tissue is described. The calculations require the AUC, AUMC, and derivatives of the plasma concentration versus time curves of the metabolite and its precursor. The method is applicable