Mean residence time in non-linear systems?
โ Scribed by Michael Weiss
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 81 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0142-2782
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A new definition of the mean residence time is proposed which includes the commonly used definition as a special case. The advantage of the new definition is that it applies for both linear and non-linear systems. Some practical advantages which follow from the new definition are discussed. Procedur
Based on disposition decomposition analysis (DDA), equations for the mean residence times (MRT) in the body are derived for a drug and its interconversion metabolite that undergo linear tissue distribution and linear or non-linear elimination from the central compartment after non-instantaneous admi
It is known that large classes of approximately-"nite-memory maps can be uniformly approximated arbitrarily well by the maps of certain non-linear structures. As an application, it was proved that time-delay networks can be used to uniformly approximate arbitrarily well the members of a large class
The relationship between the mean residence time after oral dosing or any other non-instantaneous mode of administration (MRT,,) was explored by a series of computer simultations. MRT,, was calculated from the ratio of AUMC to A U C (where A U C and A U M C are the zeroth and first statistical momen