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Phase I study of 5-fluorouracil and leucovorin by a 14-day circadian infusion in metastatic adenocarcinoma patients

✍ Scribed by Georg A. Bjarnason, Ian G. Kerr, Nancy Doyle…


Book ID
120777395
Publisher
Springer
Year
1993
Tongue
English
Weight
937 KB
Volume
33
Category
Article
ISSN
0344-5704

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Phase I study of 5-fluorouracil administ
✍ James A. Martenson; Thomas G. Shanahan; Michael J. O'Connell; Charles D. Cobau; 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 63 KB 👁 2 views

## BACKGROUND. This study was designed to assess the toxicity of pelvic radiation therapy, 5-fluorouracil (5-FU) administered by protracted venous infusion, and leucovorin. ## METHODS. Pelvic radiation therapy consisted of 50.4 -54 gray (Gy) administered in 28 -30 fractions. Systemic treatment