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Combined 5-fluorouracil and floxuridine administered as a 14-day infusion. A phase I study

โœ Scribed by Norwood Anderson; Jacob Lokich; Murray Bern; Sabina Wallach; Cherie Moore; David Williams; Vimonrat Umprayn


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
301 KB
Volume
63
Category
Article
ISSN
0008-543X

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A phase I clinical trial of combined flu
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Two consecutive Phase I trials of continuous infusion 5-fluorouracil (5-FU) or floxuridine (5-FUdR) admixed with leucovorin (LCV) were performed and involved 19 and 24 patients, respectively. The studies were carried out to identify the optimal dose rate of delivery for the two admixtures (5-FU + LC