## Abstract [^14^C]‐Sch 42427 was synthesized by two different methods, resulting in incorporation of the label in different parts of the molecule. In the first synthesis [benzyl‐α‐^14^C]‐Sch 42427 was synthesized in overall 1.7% yield via a 6 step procedure, using [^14^C]‐trimethyl sulphoxonium io
Pesticides labelled with 14C. II. Synthesis of propiconazole labelled in three different positions
✍ Scribed by Ernõ Koltai; Ferenc Kling; György Rutkai
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- French
- Weight
- 346 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
Abstract
Propiconazole was labelled with ^14^C in three different positions: in the benzene ring, in the position 5 of the dioxolane ring, and in the triazole ring. The synthesis of three new key intermediates [(m‐dichloro[U‐^14^C]benzene], 1,2,4‐[U‐^14^C]triazole, [1‐^14^C]‐pentane‐1,2‐diol) were also elaborated.
📜 SIMILAR VOLUMES
Diuron and Linuron, two herbicides, with very similar structures were labelled in their aromatic ring with I4C. The yields of the synthesis (starting from BaI4C03) was 8.5% and 4.8%, respectively. Linuron was also labelled with 14C in its urea group with 3 3 % yield.
14C labelled Metribuzine was synthetised in a five step synthesis firom sodium [l-14C]pivalate (trimethyl acetic acid) via o-brom0-[2-~~C]pinacoline (l-bromo-3,3-dimethyl-butan-2-on) and trimethyl [2-14C]pyruvic acid. The total yield was 30% (calculated on sodium pivalate).
## Abstract Hexazinone ‐ a s‐triazine type contact herbicide ‐ was labelled with ^14^C for the investigation of metabolic pathways. A convenient synthesis was elaborated for labelling of the carbon atom in the 6 position of the triazine ring. The molar activity of Hexazinone was 797.0 MBq/mmole (21
## Abstract A synthetic procedure for 2‐^14^C‐N‐nitrosohexamethyl‐eneimine 1‐aza‐l‐nitroso‐(2‐^14^C)‐cycloheptane is presented. The starting material was 1‐^14^ C‐cyclohexanone which underwent ring expansion, reduction, and finally nitrosation. The synthesis resulted in a product in good yield (68%