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The synthesis of N-nitrosohexamethyleneimine labeled with 14C in the 2-position

✍ Scribed by C. J. Granjean; D. L. Nagel; L. Wallcave; K. Phelps; G. Charnock

Publisher
John Wiley and Sons
Year
1973
Tongue
French
Weight
129 KB
Volume
9
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

A synthetic procedure for 2‐^14^C‐N‐nitrosohexamethyl‐eneimine 1‐aza‐l‐nitroso‐(2‐^14^C)‐cycloheptane is presented. The starting material was 1‐^14^ C‐cyclohexanone which underwent ring expansion, reduction, and finally nitrosation. The synthesis resulted in a product in good yield (68% overall), which is chemically and radiochemically pure.

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