ORAL TOLERANCE FOR THE TREATMENT OF AUTOIMMUNE DISEASES
β Scribed by Weiner, MD, Howard L.
- Book ID
- 125940970
- Publisher
- Annual Reviews
- Year
- 1997
- Tongue
- English
- Weight
- 71 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0066-4219
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
ral tolerance describes the observation that a state of hyporesponsiveness follows immunization with a previously fed protein. It was first described in 1911 when Wells fed hen egg proteins to guinea-pigs and found them resistant to anaphylaxis when challengedL In 1946, Chase fed guinea-pigs the con
Oral tolerance is the phenomenon of systemic, antigen specific, immunological hyporesponsiveness that results from oral administration of a protein. The mechanism by which tolerance is generated depends on the amount of antigen administered; low doses favor induction of regulatory T cells while high