Treatment of multiple sclerosis and other autoimmune diseases by oral tolerance to autoantigens
โ Scribed by Howard L. Weiner; Marika J. Hohol; Hikoaki Fukaura; Sally Kent; John Orav; Samia J. Khoury; David A. Hafler
- Book ID
- 119109313
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 135 KB
- Volume
- 56-63
- Category
- Article
- ISSN
- 0165-5728
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
ral tolerance describes the observation that a state of hyporesponsiveness follows immunization with a previously fed protein. It was first described in 1911 when Wells fed hen egg proteins to guinea-pigs and found them resistant to anaphylaxis when challengedL In 1946, Chase fed guinea-pigs the con
Oral tolerance is the phenomenon of systemic, antigen specific, immunological hyporesponsiveness that results from oral administration of a protein. The mechanism by which tolerance is generated depends on the amount of antigen administered; low doses favor induction of regulatory T cells while high