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Oral Tolerance: Immunologic Mechanisms and Treatment of Animal and Human Organ-Specific Autoimmune Diseases by Oral Administration of Autoantigens

✍ Scribed by Weiner, H L; Friedman, A; Miller, A; Khoury, S J; Al-Sabbagh, A; Santos, L; Sayegh, M; Nussenblatt, R B; Trentham, D E; Hafler, D A

Book ID
120411822
Publisher
Annual Reviews
Year
1994
Tongue
English
Weight
770 KB
Volume
12
Category
Article
ISSN
0732-0582

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πŸ“œ SIMILAR VOLUMES

Oral tolerance: immune mechanisms and tr
Oral tolerance: immune mechanisms and treatment of autoimmune diseases
✍ Howard L. Weiner πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 English βš– 909 KB

ral tolerance describes the observation that a state of hyporesponsiveness follows immunization with a previously fed protein. It was first described in 1911 when Wells fed hen egg proteins to guinea-pigs and found them resistant to anaphylaxis when challengedL In 1946, Chase fed guinea-pigs the con

Oral tolerance: Elucidation of mechanism
Oral tolerance: Elucidation of mechanisms and application to treatment of autoimmune diseases
✍ Elizabeth Fowler; Howard L. Weiner πŸ“‚ Article πŸ“… 1997 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 209 KB

Oral tolerance is the phenomenon of systemic, antigen specific, immunological hyporesponsiveness that results from oral administration of a protein. The mechanism by which tolerance is generated depends on the amount of antigen administered; low doses favor induction of regulatory T cells while high