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New selenyl linker for solid-phase synthesis of dehydropeptides

✍ Scribed by Kazuhiko Nakamura; Yuki Ohnishi; Eiji Horikawa; Takeo Konakahara; Masato Kodaka; Hiroaki Okuno

Publisher: Elsevier Science
Year: 2003
Tongue: French
Weight: 214 KB
Volume: 44
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(03)01309-1

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✦ Synopsis

A novel linker possessing selenocyanate and masked carboxylic acid was developed for the solid-phase synthesis of dehydropeptides. This linker was used to demonstrate the synthesis of the model compound of RGD-conjugated dehydropeptide.

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