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Linkers for Solid-Phase Synthesis

✍ Scribed by Kerstin Knepper; Carmen Gil; Stefan Brase


Publisher
John Wiley and Sons
Year
2005
Weight
8 KB
Volume
36
Category
Article
ISSN
0931-7597

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## Abstract For Abstract see ChemInform Abstract in Full Text.

ChemInform Abstract: Linkers for Solid-P
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A new and cost-effective linker for the generation of carboxylic acid end groups on Multipin supports (SynPhaseβ„’ crowns) has been developed. Synthesis of the linker was based on modification of grafted polystyrene (PS) crowns to generate a hydroxyethyl moiety which is acid labile in 10 -20% trifluor