𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Lack of Activation of the Unfolded Protein Response in Mouse and Cellular Models of Niemann-Pick Type C Disease

✍ Scribed by Klein, Andres; Mosqueira, Matías; Martínez, Gabriela; Robledo, Fermín; González, Marcela; Caballero, Benjamín; Cancino, Gonzalo I.; Alvarez, Alejandra R.; Hetz, Claudio; Zanlungo, Silvana

Book ID
120333337
Publisher
S. Karger AG
Year
2010
Tongue
English
Weight
260 KB
Volume
8
Category
Article
ISSN
1660-2854

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Decreased purinergic inhibition of synap
Decreased purinergic inhibition of synaptic activity in a mouse model of Niemann-Pick disease type C
✍ Su-ya Zhou; Shu-jun Xu; Ying-gang Yan; Hui-mei Yu; Shu-cai Ling; Jian-hong Luo 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 715 KB

## Abstract Niemann‐Pick disease type C (NPC) is a progressive neurodegenerative disorder characterized by accumulation of free cholesterol in lysosomes, mainly due to a mutation in the NPC1 gene. The pathophysiological basis of the neural disorders in NPC, however, is not well understood. We found