✦ LIBER ✦

A C57BL/KsJ mouse model of Niemann-Pick disease (spm) belongs to the same complementation group as the major childhood type of Niemann-Pick disease type C

✍ Scribed by S. Akaboshi; Tamami Yano; Shigeki Miyawaki; Kousaku Ohno; Kenzo Takeshita

Publisher: Springer
Year: 1997
Tongue: English
Weight: 111 KB
Volume: 99
Category: Article
ISSN: 0340-6717
DOI: 10.1007/s004390050370

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Early-lethal pulmonary form of Niemann-P

Early-lethal pulmonary form of Niemann-Pick type C disease belonging to a second, rare genetic complementation group

✍ O. Schofer; B. Mischo; W. Püschel; K. Harzer; M. T. Vanier 📂 Article 📅 1998 🏛 Springer 🌐 English ⚖ 417 KB

Decreased estradiol release from astrocy

Decreased estradiol release from astrocytes contributes to the neurodegeneration in a mouse model of Niemann-Pick disease type C

✍ Gang Chen; Hai-Min Li; Yi-Ren Chen; Xiao-Song Gu; Shumin Duan 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 532 KB

## Abstract Niemann‐Pick disease type C (NPC) is a deadly neurodegenerative disease often caused by mutation in a gene called NPC1, which results in the accumulation of unesterified cholesterol and glycosphingolipids in the endosomal–lysosomal system. Most studies on the mechanisms of neurodegenera