K-ras mutations in human adenocarcinoma
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K. Husgafvel-Pursiainen; P. Hackman; M. RidanpÀÀ; S. Anttila; A. Karjalainen; T.
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Article
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1993
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John Wiley and Sons
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French
β 784 KB
## Abstract We investigated point mutational activation of the __ras__ genes (Kβ__ras__ codons 12, 13 and 61; Nβ__ras__ codons 12, 13 and 61; Hβ__ras__ codons 12 and 61) in primary, resected lung cancer by dot blotting and oligonucleotide hybridization. Kβ__ras__ mutations were found in 14 (29%) of