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K-ras mutations in human adenocarcinoma of the lung: Association with smoking and occupational exposure to asbestos


Book ID
122448606
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
302 KB
Volume
10
Category
Article
ISSN
0169-5002

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K-ras mutations in human adenocarcinoma
✍ K. Husgafvel-Pursiainen; P. Hackman; M. RidanpÀÀ; S. Anttila; A. Karjalainen; T. πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 French βš– 784 KB

## Abstract We investigated point mutational activation of the __ras__ genes (K‐__ras__ codons 12, 13 and 61; N‐__ras__ codons 12, 13 and 61; H‐__ras__ codons 12 and 61) in primary, resected lung cancer by dot blotting and oligonucleotide hybridization. K‐__ras__ mutations were found in 14 (29%) of