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Mutations in the p53 gene in lung cancer are associated with cigarette smoking and asbestos exposure


Book ID
122003089
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
140 KB
Volume
13
Category
Article
ISSN
0169-5002

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Validated markers are needed to identify operable lung cancer patients with poor prognosis. About one-half of nonsmall-cell lung cancers (NSCLCs) carry a mutation in the p53 tumor-suppressor gene. We examined 101 NSCLC patients for surgical stage, completeness of resection, tobacco smoking, asbestos