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P53 gene mutations are associated with poor prognosis in adenocarcinoma of the lung

✍ Scribed by E. Jassem; R. Rosell; M. Monzo; J.-M. De Anta; J. Skokowski; A. Badzio; A. Roszkiewicz; J. Jassem


Book ID
117667953
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
160 KB
Volume
35
Category
Article
ISSN
0959-8049

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p16 inactivation in small-sized lung ade
✍ Beniyo Kawabuchi; Sachiko Moriyama; Mitsugu Hironaka; Takeshi Fujii; Morio Koike πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 French βš– 105 KB

p16, an inhibitor of cell cycle machinery, is frequently inactivated in non-small cell carcinoma of the lung (NSCCL). To clarify the significance of p16 inactivation in the progression of lung adenocarcinoma, we immunohistochemically evaluated p16 protein status and Rb, p53 and cyclin D1 expression