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Supplement 3: Environmental Mutagenesis in Human Populations at Risk || Interaction between Smoking and Asbestos in Human Lung Adenocarcinoma: Role of K-ras Mutations

✍ Scribed by Harri Vainio, Kirsti Husgafvel-Pursiainen, Sisko Anttila, Antti Karjalainen, Peter Hackman and Timo Partanen


Book ID
124306051
Publisher
Environmental Health Information Service
Year
1993
Tongue
English
Weight
708 KB
Volume
101
Category
Article
ISSN
0091-6765

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K-ras mutations in human adenocarcinoma
✍ K. Husgafvel-Pursiainen; P. Hackman; M. RidanpÀÀ; S. Anttila; A. Karjalainen; T. πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 French βš– 784 KB

## Abstract We investigated point mutational activation of the __ras__ genes (K‐__ras__ codons 12, 13 and 61; N‐__ras__ codons 12, 13 and 61; H‐__ras__ codons 12 and 61) in primary, resected lung cancer by dot blotting and oligonucleotide hybridization. K‐__ras__ mutations were found in 14 (29%) of