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Juvenile rheumatoid arthritis and the trimolecular complex (hla, t cell receptor, and antigen)

✍ Scribed by Alexei A. Grom; Edward H. Giannini; David N. Glass

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
679 KB
Volume
37
Category
Article
ISSN
0004-3591

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HLA and T Cell Receptor Polymorphisms in
HLA and T Cell Receptor Polymorphisms in Pauciarticular-Onset Juvenile Rheumatoid Arthritis
✍ Barbara S. Nepom; Uma Malhotra; David A. Schwarz; James W. Nettles; Jane G. Scha πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 755 KB

The immunogenetic basis of pauciarticular-onset juvenile rheumatoid arthritis is unclear. We therefore analyzed the HLA and T cell receptor genes present in a clinically well-defined group of patients. We found that the DR8 haplotype contributes most of the HLAassociated risk, although alleles at ot