Abnormal t suppressor cell function in juvenile rheumatoid arthritis
β Scribed by Earl D. Silverman; Catherine Somma; Manzoor M. Khan; Kenneth L. Melmon; Edgar G. Engleman
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 630 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0004-3591
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π SIMILAR VOLUMES
To assess the extent of physical disability in juvenile rheumatoid arthritis (JRA), classified according to subtype, and whether synovitis or flexion contractures are present on examination. Methods. This retrospective study included 88 JRA patients and 50 controls without musculoskeletal disease.
## Abstract ## Objective To characterize local bone geometry, density, and strength, using peripheral quantitative computed tomography (pQCT), compared with general bone characteristics as measured using dual xβray absorptiometry (DXA), and to assess their relationship to diseaseβrelated factors i
The immunogenetic basis of pauciarticular-onset juvenile rheumatoid arthritis is unclear. We therefore analyzed the HLA and T cell receptor genes present in a clinically well-defined group of patients. We found that the DR8 haplotype contributes most of the HLAassociated risk, although alleles at ot