A simple and highly efficient stereoselective total synthesis of cytotoxic agent sporiolide A has been achieved starting from D-mannitol; the strategy of synthesis utilizes stereoselective zinc-mediated allylation, aldol coupling and ring-closing metathesis as key steps.
✦ LIBER ✦
First stereoselective synthesis of cytotoxic (−)-kunstleramide
✍ Scribed by Purushotham Reddy, S.; Venkateswarlu, Y.
- Book ID
- 120500375
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- French
- Weight
- 409 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0040-4039
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