An enantiospecific synthesis of the antitumor marine sponge metabolite puupehedione (2a) and its C 8 -epimer 2b as their methylenedioxy derivatives 8a and 8b was achieved through concomitant O-allyl deprotection and electrocyclization of 20 derived from (-)-carvone.
An Efficient Stereoselective Synthesis of Cytotoxic 8-Epipuupehedione
✍ Scribed by Armstrong, Veronica; Barrero, Alejandro F.; Alvarez-Manzaneda, Enrique J.; Cortés, Manuel; Sepúlveda, Beatriz
- Book ID
- 118272406
- Publisher
- American Chemical Society
- Year
- 2003
- Tongue
- English
- Weight
- 50 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0163-3864
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