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Expression of Cyclooxygenase-1 and -2 in Human Breast Cancer

✍ Scribed by Norio Yoshimura; Hajime Sano; Masahiko Okamoto; Kiyokazu Akioka; Hidetaka Ushigome; Yayoi Kadotani; Rikio Yoshimura; Shuji Nobori; Atsushi Higuchi; Yoshihiro Ohmori; Kenji Nakamura

Book ID
113047879
Publisher
Springer
Year
2003
Tongue
English
Weight
291 KB
Volume
33
Category
Article
ISSN
1436-2813

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## Abstract ## Introduction The cyclooxygenase‐2 (COX‐2), responsible for the conversion of arachidonic acid into prostaglandin (PG) E2, is known to increase intracellular cAMP and estrogen production in malignant breast tissue. The aromatase enzyme complex is responsible for local production of e