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Levels of expression of lipoxygenases and cyclooxygenase-2 in human breast cancer

✍ Scribed by Wen G. Jiang; Anthony Douglas-Jones; Robert E. Mansel

Book ID
117641877
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
335 KB
Volume
69
Category
Article
ISSN
0952-3278

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## Abstract ## Introduction The cyclooxygenase‐2 (COX‐2), responsible for the conversion of arachidonic acid into prostaglandin (PG) E2, is known to increase intracellular cAMP and estrogen production in malignant breast tissue. The aromatase enzyme complex is responsible for local production of e