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Correlation of aromatase and cyclooxygenase gene expression in human breast cancer specimens

✍ Scribed by Robert W. Brueggemeier; Anne L. Quinn; Michelle L. Parrett; Farahnaz S. Joarder; Randall E. Harris; Fredika M. Robertson

Book ID
117469417
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
185 KB
Volume
140
Category
Article
ISSN
0304-3835

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## Abstract ## Introduction The cyclooxygenase‐2 (COX‐2), responsible for the conversion of arachidonic acid into prostaglandin (PG) E2, is known to increase intracellular cAMP and estrogen production in malignant breast tissue. The aromatase enzyme complex is responsible for local production of e