## Abstract ## Introduction The cyclooxygenaseβ2 (COXβ2), responsible for the conversion of arachidonic acid into prostaglandin (PG) E2, is known to increase intracellular cAMP and estrogen production in malignant breast tissue. The aromatase enzyme complex is responsible for local production of e
Up-regulation of cyclooxygenase-2 gene expression correlates with tumor angiogenesis in human breast cancer
β Scribed by Zhi-jun Dai; Xi-jing Wang; Xiao-xu Liu; Hua-feng Kang; Jina-tao Jiang; Hai-tao Guan; Shu-qun Zhang; Xing-huan Xue; Feng-jie Xue
- Publisher
- Chinese Anti-Cancer Association
- Year
- 2003
- Tongue
- English
- Weight
- 296 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1000-9604
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## Abstract ## Background and Objectives Elevated expression of cyclooxygenaseβ2 (COXβ2) has been established to be a feature of breast cancer. There has been inconsistency in the literature regarding the precise significance of thisβsome studies have found no clinicopathological relevance at all,