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Correlation of cyclooxygenase-2 (COX-2) and aromatase expression in human endometrial cancer: Tissue microarray analysis

✍ Scribed by Jeffrey M. Fowler; Nilsa Ramirez; David E. Cohn; Nicole Kelbick; James Pavelka; Inbar Ben-Shachar; Carl Morrison

Book ID
113429081
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
501 KB
Volume
192
Category
Article
ISSN
1097-6868

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## Abstract ## Introduction The cyclooxygenase‐2 (COX‐2), responsible for the conversion of arachidonic acid into prostaglandin (PG) E2, is known to increase intracellular cAMP and estrogen production in malignant breast tissue. The aromatase enzyme complex is responsible for local production of e