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Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues

✍ Scribed by Gary P. O'Neill; Anthony W. Ford-Hutchinson

Book ID: 115927450
Publisher: Elsevier Science
Year: 1993
Tongue: English
Weight: 663 KB
Volume: 330
Category: Article
ISSN: 0014-5793
DOI: 10.1016/0014-5793(93)80263-t

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## Abstract ## Introduction The cyclooxygenase‐2 (COX‐2), responsible for the conversion of arachidonic acid into prostaglandin (PG) E2, is known to increase intracellular cAMP and estrogen production in malignant breast tissue. The aromatase enzyme complex is responsible for local production of e