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Enhancement of hepatitis B surface antigen production by adenosine 5′-monophosphate in culture of recombinant Chinese hamster ovary cells

✍ Scribed by Weiwen Luo; Xiangming Sun; Xiaoping Yi; Yuanxing Zhang

Book ID
115031790
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
211 KB
Volume
100
Category
Article
ISSN
1389-1723

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## Abstract The production and specific productivity of hepatitis B surface antigen (HBsAg) in recombinant Chinese hamster ovary (CHO) cells were increased by 81% and threefold, respectively, when supplemented with 1.5% dimethyl sulfoxide (DMSO) in the culture medium. To investigate the mechanism o