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Decreased binding of epidermal growth factor to BALB/c 3T3 mutant cells defective in glycoprotein synthesis

✍ Scribed by PRATT, ROBERT M.; PASTAN, IRA

Book ID
109708762
Publisher
Nature Publishing Group
Year
1978
Tongue
English
Weight
344 KB
Volume
272
Category
Article
ISSN
0028-0836

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Binding, internalization, and degradatio
Binding, internalization, and degradation of epidermal growth factor by Balb 3T3 and BP3T3 cells: Relationship to cell density and the stimulation of cell proliferation
✍ Kenneth D. Brown; Yun-Chi Yeh; Robert W. Holley πŸ“‚ Article πŸ“… 1979 πŸ› John Wiley and Sons 🌐 English βš– 852 KB

## Abstract Epidermal growth factor (EGF) stimulates the growth of both benzo[a]pyrene‐transformed Balb 3T3 cells (BP3T3) and untransformed Balb 3T3 cells. We describe here the binding, internalization, and degradation of [^125^I]‐EGF by BP3T3 cells and 3T3 cells. Binding of [^125^I]‐EGF reaches a