𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Aberrant MGMT (O6-methylguanine-DNA methyltransferase) promoter methylation in choroid plexus tumors

✍ Scribed by Martin Hasselblatt; Jörg Mühlisch; Brigitte Wrede; Birgit Kallinger; Astrid Jeibmann; Ove Peters; Tezer Kutluk; Johannes E. A. Wolff; Werner Paulus; Michael C. Frühwald

Publisher
Springer US
Year
2008
Tongue
English
Weight
345 KB
Volume
91
Category
Article
ISSN
0167-594X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Methylation of the O6-methylguanine-DNA
Methylation of the O6-methylguanine-DNA methyltransferase promoter suppresses expression in mouse skin tumors and varies with the tumor induction protocol
✍ Rana Abdel-Fattah; Adam Glick; Ishtiaq Rehman; Patrick Maiberger; Henry Hennings 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 212 KB

## Abstract Hypermethylation of CpG sites within the promoter region of the __O^6^‐methylguanine‐DNA methyltransferase__ (__MGMT__) gene occurs frequently in human cancer, preventing both MGMT expression and repair of alkylation damage. To assess the role of MGMT in the development of mouse skin tu