## Abstract The tri‐peptide [^14^C]‐glutathione ([^14^C]‐GSH) was synthesized in a single step by GSH synthetase catalyzed reaction of L‐γ‐glutamyl‐L‐cysteine and [^14^C]‐glycine. Preparative reverse phase HPLC afforded [^14^C]‐GSH in 30% yield and 98% purity. Preparation of GSH synthetase from E.
A simple, one-step synthesis of 1-14C-acetylhydrazine
✍ Scribed by P. Mathiaparanam; L. T. Wong; B. H. Thomas
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- French
- Weight
- 220 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
Abstract
A synthesis of 1‐^14^C‐acetylhydrazine by acetylation of hydrazine using 1‐ ^14^C‐ethyl acetate and a catalytic amount of activated alumina is described.
📜 SIMILAR VOLUMES
## Abstract Condensation between 1‐trimethylsilyloxy‐3‐butanone and trimethylsilyl __[2‐^14^C]__acetate gave (±) [2‐^14^C]mevalonolactone in one step.
## Abstract A convenient method of synthesis of 2, 6‐diaminopinelic / 1, 7 ^14^C / acid / DAP / has been elaborated. Glutaric aldehyde and K^14^CN produced the dicyanhydrine which was converted without izolation into the dihydantoine derivative of DAP by treatment with NH~4~HCO~3~. Hydrolisis /H~2~
## Abstract Propionic‐3‐^14^C acid was prepared by methylation of tricarbethoxymethane and subsequent hydrolysis. This method avoids the problems of malonic ester synthesis. A pure monoalkyl derivative was obtained.
Conditions were found for almost quantitative carboxylation of n-hexyllithium with l4CO2 to afford lithium [1-l4C] heptanoate. It was then possible to perform the reaction sequence lithium [1-l4C] heptanoate --+ [l-14C] heptan-1-01 + 1-bromo [l-14q heptane in one flask without isolation of intermed