## Abstract The synthesis of 3‐[ 2′,4′,5′‐triethoxybenzoyl‐(carbonyl‐^14^C)]‐propionic acid (VII) is described. Chloroacetonitrile‐^14^C (IV) was prepared from chloroacetic‐1‐^14^C acid (I) according to the well‐known procedure. IV was reacted with 1,2,4‐triethoxybenzene in the presence of ZnCl~2~
A simple synthesis of propionic-3-14C acid
✍ Scribed by E. Koltai; D. Bánfi
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- French
- Weight
- 159 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
Abstract
Propionic‐3‐^14^C acid was prepared by methylation of tricarbethoxymethane and subsequent hydrolysis. This method avoids the problems of malonic ester synthesis. A pure monoalkyl derivative was obtained.
📜 SIMILAR VOLUMES
## Abstract The title product was labelled with ^14^C at the ketone group, from 3‐methoxybromobenzene in six steps. Complete synthetic techniques of the labelled drug are presented.
Preparation of 14C labeled p-aminoisobutyric acid (3 Amino-2 methyl-propionic acid, 314C) \* In the course of studies on the catabolism of thymidine the need emerged to study in greater detail its metabolite (l), p aminoisobutyric acid (BAIBA). This substance, labeled with 14C in the 3-C position,
## Abstract A convenient method of synthesis of 2, 6‐diaminopinelic / 1, 7 ^14^C / acid / DAP / has been elaborated. Glutaric aldehyde and K^14^CN produced the dicyanhydrine which was converted without izolation into the dihydantoine derivative of DAP by treatment with NH~4~HCO~3~. Hydrolisis /H~2~