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Preparation of 14C labeled β-aminoisobutyric acid (3 Amino-2 methyl-propionic acid, 314C)

✍ Scribed by J. H. Lukas; G. B. Gerber

Publisher
John Wiley and Sons
Year
1965
Tongue
French
Weight
81 KB
Volume
1
Category
Article
ISSN
0022-2135

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✦ Synopsis

Preparation of 14C labeled p-aminoisobutyric acid (3 Amino-2 methyl-propionic acid, 314C) *

In the course of studies on the catabolism of thymidine the need emerged to study in greater detail its metabolite (l), p aminoisobutyric acid (BAIBA). This substance, labeled with 14C in the 3-C position, was synthesized by the following procedure, which represents a modification of the synthesis of inactive BAIBA (2) :

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