## Abstract The synthesis of mevalonolactone with ^13^C‐labels at positions 2 and 3 is reported. Hydrolysis of methyl 3‐hydroxy‐3‐methyl‐5,5‐dimethoxy‐valerate‐2,3‐^13^C~2~ to the aldehydo acid followed by reduction with sodium borohydride yielded the title compound. The material is useful as a sub
Synthesis of (±) [2-14C]mevalonolactone in one step
✍ Scribed by Asoke Banerji; Govind P. Kalena
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- French
- Weight
- 136 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Condensation between 1‐trimethylsilyloxy‐3‐butanone and trimethylsilyl __[2‐^14^C]__acetate gave (±) [2‐^14^C]mevalonolactone in one step.
📜 SIMILAR VOLUMES
## Abstract A synthesis of 1‐^14^C‐acetylhydrazine by acetylation of hydrazine using 1‐ ^14^C‐ethyl acetate and a catalytic amount of activated alumina is described.
The chemical synthesis of double labelled mevalonolactone with carbon l a c at positions C-4 and C-6 is reported.
## Abstract A convenient method of preparing 2‐octyl (4‐amino‐3,5‐dichloro‐6‐fluoro‐2‐pyridinyloxy‐2,6‐^14^C)acetate from glutarimide‐2,6‐^14^C is described. The process includes a novel one‐step conversion of glutarimide‐2,6‐^14^C to pentachloropyridine‐2,6‐^14^C.
The total synthesis of the title compound from pyruvic aldehyde dimethyl acetal and ethyl [Z-lfClacetate is reported.