A novel reaction of ketone arylhydrazones with nitric oxide
β Scribed by Desuo Yang; Liandi Lei; Zhongquan Liu; Longmin Wu
- Book ID
- 108284688
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 175 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
## Abstract Reactions of aldehyde arylhydrazones (**1**) with nitric oxide in the presence of trace oxygen gave exclusively (__E__)βC(1β²)βnitrohydrazones (**2**) in high yield. The structure of products was confirmed by NMR, IR, MS and Xβray crystallography. The reaction is assumed to be initiated
## Abstract The unexpected reaction leads exclusively to (E)βnitrohydrazones (II); azoβcompounds are not obtained.
Amides were allowed to react with nitric oxide in aprotic and non-ethereal solvents to give the corresponding N-nittoso derivatives. The reaction was accelerated by addition of oxygen. The solvent effect revealed that the reaction did not proceed in the presence of protic media.
Reaction of nitric acid vlth unsaturated steroids under mild conditions Is known for a very long time and several authors have carried aut this reaction to prepare nltrosterolds l-3. In aw hands this reaction yielded a novel pro&et whose structure and mode of formation Is now elucidated.
Reaction of Nitric Oxide with Amines. -NO and NO/O2, respectively, are found to be useful reagents for the aromatization of Hantzsch dihydropyridines (β (II)) and deamination of aromatic amines (β (VI)). -