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A NOVEL APPROACH TO SOLID PHASE CHEMICAL SYNTHESIS OF OLIGONUCLEOTIDE mRNA CAP ANALOGS

✍ Scribed by Jemielity, Jacek; Heinonen, Petri; Lönnberg, Harri; Darzynkiewicz, Edward

Book ID
118208984
Publisher
Taylor and Francis Group
Year
2005
Tongue
English
Weight
296 KB
Volume
24
Category
Article
ISSN
0732-8311

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Solid-phase synthesis of Agel 416; a nov
Solid-phase synthesis of Agel 416; a novel approach to modified polyamines
✍ Neal D Hone; Lloyd J Payne 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 112 KB

The synthesis of Agel 416, an acylpolyamine derived from the spider Agenolopsis aperta, has been achieved on solid support. Stepwise synthesis of the polyamine chain was accomplished using N-protected amino alcohols and the Fukuyama±Mitsunobu reaction.