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A Discovery-Oriented Approach to Solid-Phase Peptide Synthesis

✍ Scribed by Bockman, Matthew R.; Miedema, Christopher J.; Brennan, Brian B.


Book ID
115446182
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
322 KB
Volume
89
Category
Article
ISSN
0021-9584

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## Abstract A strategy was developed to directly assemble 4‐amino‐1,2,4,5‐tetrahydro‐indolo[2,3‐__c__]‐azepin‐3‐ones on solid‐phase‐supported peptide sequences. Fmoc‐ and Boc‐based strategies were investigated. The Fmoc‐strategy approach strongly depends on the peptide sequence being synthesized wh