## Abstract A convenient method for the synthesis of ^18^F‐2‐deoxy‐2‐fluoro‐D‐glucose (4) and ^18^F‐2‐deoxy‐2‐fluoro‐D‐mannose (8) by the direct fluorination of 3,4,6‐tri‐0‐acetyl‐D‐glucal with ^18^F‐F~2~ is described. ^14^C‐2‐deoxy‐2‐fluoro‐D‐glucose has been synthesized from ^14^C‐3,4,6‐tri‐0‐ace
2-deoxy-2-[18F]-fluoro-3-o-methyl-D-glucose synthesis and animal biodistribution studies
✍ Scribed by S. Levy; E. Livni; D.R. Elmaleh; D.A. Varnum; G.L. Brownell
- Publisher
- Elsevier Science
- Year
- 1983
- Weight
- 240 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0020-708X
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📜 SIMILAR VOLUMES
## Abstract We have synthesized __β__‐O‐D‐galactopyranosyl‐(1,4′)‐2′‐[^18^F]fluoro‐2′‐deoxy‐D‐glucopyranose (2′‐[^18^F]fluorodeoxylactose, ^18^FDL) using an enzymatic method starting from ^18^FDG in order to evaluate this compound with regard to its usefulness for __in vivo__ visualization of the e
18F labelled compounds. Thus, a synthetic route to ("F)2-Deoxy-2-fluoro-~glucose was studied which should run as simple and hot-cell-friendly as possible and shc~uld deliver the sugar with high yield and free of diastereomers, even by use of high I8F acitivities