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Design and Synthesis of 2-Deoxy-2-[18F]fluoro-D-glucose

✍ Scribed by Joanna S. Fowler; Tatsuo Ido

Publisher: John Wiley and Sons
Year: 2005
Weight: 15 KB
Volume: 36
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200517262

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## Abstract A convenient method for the synthesis of ^18^F‐2‐deoxy‐2‐fluoro‐D‐glucose (4) and ^18^F‐2‐deoxy‐2‐fluoro‐D‐mannose (8) by the direct fluorination of 3,4,6‐tri‐0‐acetyl‐D‐glucal with ^18^F‐F~2~ is described. ^14^C‐2‐deoxy‐2‐fluoro‐D‐glucose has been synthesized from ^14^C‐3,4,6‐tri‐0‐ace

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