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New high-yield synthesis of 18F-labelled 2-deoxy-2-fluoro-D-glucose

✍ Scribed by Mirko Diksic; Dean Jolly

Publisher
Elsevier Science
Year
1983
Weight
371 KB
Volume
34
Category
Article
ISSN
0020-708X

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📜 SIMILAR VOLUMES

Labeled 2-deoxy-D-glucose analogs. 18F-l
Labeled 2-deoxy-D-glucose analogs. 18F-labeled 2-deoxy-2-fluoro-D-glucose, 2-deoxy-2-fluoro-D-mannose and 14C-2-deoxy-2-fluoro-D-glucose
✍ T. Ido; C-N. Wan; V. Casella; J. S. Fowler; A. P. Wolf; M. Reivich; D. E. Kuhl 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 French ⚖ 337 KB 👁 1 views

## Abstract A convenient method for the synthesis of ^18^F‐2‐deoxy‐2‐fluoro‐D‐glucose (4) and ^18^F‐2‐deoxy‐2‐fluoro‐D‐mannose (8) by the direct fluorination of 3,4,6‐tri‐0‐acetyl‐D‐glucal with ^18^F‐F~2~ is described. ^14^C‐2‐deoxy‐2‐fluoro‐D‐glucose has been synthesized from ^14^C‐3,4,6‐tri‐0‐ace

Synthesis of (18F)2-deoxy-2-fluoro-D-glu
Synthesis of (18F)2-deoxy-2-fluoro-D-glucose using high 81F activities
✍ Mario Argentini; Thomas Mäder; Regin Weinreich 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 French ⚖ 50 KB

18F labelled compounds. Thus, a synthetic route to ("F)2-Deoxy-2-fluoro-~glucose was studied which should run as simple and hot-cell-friendly as possible and shc~uld deliver the sugar with high yield and free of diastereomers, even by use of high I8F acitivities