A novel synthesis of pyrrolidine containing tx-hydroxyamide core structures as inhibitors for HIV protease is developed by employing polyaniline supported cobalt (II) salen catalysed formation of the epoxide from cinnamoylamides of L-proline followed by its opening with anilines at ambient condition
✦ LIBER ✦
α-hydroxyamide derived aminodiols as potent inhibitors of hiv protease
✍ Scribed by Saleem Ahmad; Aaila Ashfaq; Masud Alam; Gregory S. Bisacchi; Ping Chen; Peter T.W. Cheng; Jill A. Greytok; Mark A. Hermsmeier; Pin-Fang Lin; Karen A. Lis; Zoeb Merchant; Toomas Mitt; Mark Skoog; Steven H. Spergel; Joseph A. Tino; Gregory D. Vite; Richard J. Colonno; Robert Zahler; Joel C. Barrish
- Book ID
- 103983020
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 321 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0960-894X
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