✦ LIBER ✦

Polyaniline supported cobalt(II) salen catalysed synthesis of pyrrolidine containing α-hydroxyamide core structures as inhibitors for HIV proteases

✍ Scribed by T. Punniyamurthy; Javed Iqbal

Publisher: Elsevier Science
Year: 1997
Tongue: French
Weight: 178 KB
Volume: 38
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(97)00902-7

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✦ Synopsis

A novel synthesis of pyrrolidine containing tx-hydroxyamide core structures as inhibitors for HIV protease is developed by employing polyaniline supported cobalt (II) salen catalysed formation of the epoxide from cinnamoylamides of L-proline followed by its opening with anilines at ambient condition. 6

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ChemInform Abstract: Polyaniline-Support

ChemInform Abstract: Polyaniline-Supported Cobalt(II) Salen Catalyzed Synthesis of Pyrrolidine Containing α-Hydroxyamide Core Structures as Inhibitors for HIV Proteases.

✍ T. PUNNIYAMURTHY; J. IQBAL 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 2 views

Polyaniline-Supported Cobalt(II) Salen Catalyzed Synthesis of Pyrrolidine Containing α-Hydroxyamide Core Structures as Inhibitors for HIV Proteases. -A general and efficient approach to potentially useful inhibitors of HIV protease is developed. The polymer-supported catalyst PASC catalyzes the epo