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Two-stage designs optimal under the alternative hypothesis for phase II cancer clinical trials

โœ Scribed by A.P. Mander; S.G. Thompson


Book ID
116350916
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
332 KB
Volume
31
Category
Article
ISSN
1551-7144

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Optimal three-stage designs for phase II
โœ T. Timothy Chen ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 136 KB ๐Ÿ‘ 2 views

The objective of a phase II cancer clinical trial is to screen a treatment that can produce a similar or better response rate compared to the current treatment results. This screening is usually carried out in two stages as proposed by Simon. For ineffective treatment, the trial should terminate at